February 6, 2013
New Guidelines for Amyloid PET Imaging
By: Pauline Anderson
January 28, 2013 - A new document aims to provide guidance on appropriate and inappropriate use of amyloid β (Aβ) positron emission tomography (PET) imaging in helping to clarify a diagnosis of Alzheimer's disease (AD) or frontotemporal dementia.
The guidelines were developed by a task force of experts in the fields of imaging, neurology, and dementing diseases that was struck by the Alzheimer's Association and the Society of Nuclear Medicine and Molecular Imaging (SNMMI).
The document outlines 3 scenarios in which a determination of amyloid positivity or negativity would increase the level of diagnostic certainty and influence the plan for patient management.
Task force members developed the guidelines after a detailed evidence-based review of the literature. The recommendations are published online January 28 in Alzheimer's & Dementia: The Journal of the Alzheimer's Association and The Journal of Nuclear Medicine.